Small US trial looks at body's ability to fight HIV
March 9, 2012 A new approach to coaxing the body to fight HIV without antiretroviral drugs has shown some success in almost half the patients enrolled in a small study, US researchers said Wednesday.
Twenty HIV-positive volunteers in Pennsylvania were asked to stop taking their drug therapy and submit instead to weekly doses of interferon-alpha, an antiviral chemical produced by the human immune system.
The treatment kept HIV under control in nine of the 20 patients at the 12-week mark, and appeared to decrease the amount of HIV present in cells that harbor the infection, known as reservoirs.
The trial was meant to last 24 weeks or until a person's HIV levels either rose or T-cells dropped to a certain level, at which point the subjects were to resume their antiretroviral treatment.
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