Could Andrew Wakefield Have Been Correct?

Could Andrew Wakefield Have Been Correct?

The British medical authorities have tried their best to discredit and destroy Dr. Andrew Wakefield for drawing a connection between the MMR vaccine, gastrointestinal disease, and autism  – his research paper was retracted, he was accused of fraud, he was stripped of his medical license and prevented from working as a doctor in England.  More than 12 large-scale epidemiological studies failed to find evidence of this link.  But is it possible they weren’t really looking for the evidence?  That may be starting to change.  Now in a study at Columbia University, researchers have found a link between GI disturbances and high levels of a certain species of GI bacteria in children with autism.  Interestingly, the researchers did not find this same bacteria in children who do not have autism.

 

Application of Novel PCR-Based Methods for Detection, Quantitation, and Phylogenetic Characterization of Sutterella Species in Intestinal Biopsy Samples from Children with Autism and Gastrointestinal Disturbances

1. ,
2. Mady Hornig,
3. Tanmay Parekh, and

ABSTRACT

Gastrointestinal disturbances are commonly reported in children with autism and may be associated with compositional changes in intestinal bacteria. In a previous report, we surveyed intestinal microbiota in ileal and cecal biopsy samples from children with autism and gastrointestinal dysfunction (AUT-GI) and children with only gastrointestinal dysfunction (Control-GI). Our results demonstrated the presence of members of the family Alcaligenaceae in some AUT-GI children, while no Control-GI children had Alcaligenaceae sequences. Here we demonstrate that increased levels of Alcaligenaceae in intestinal biopsy samples from AUT-GI children result from the presence of high levels of members of the genus Sutterella. We also report the first Sutterella-specific PCR assays for detecting, quantitating, and genotyping Sutterella species in biological and environmental samples. Sutterella 16S rRNA gene sequences were found in 12 of 23 AUT-GI children but in none of 9 Control-GI children. Phylogenetic analysis revealed a predominance of either Sutterella wadsworthensis or Sutterella stercoricanis in 11 of the individual Sutterella-positive AUT-GI patients; in one AUT-GI patient, Sutterella sequences were obtained that could not be given a species-level classification based on the 16S rRNA gene sequences of known Sutterella isolates. Western immunoblots revealed plasma IgG or IgM antibody reactivity to Sutterella wadsworthensis antigens in 11 AUT-GI patients, 8 of whom were also PCR positive, indicating the presence of an immune response to Sutterella in some children.

IMPORTANCE Autism spectrum disorders affect ~1% of the population. Many children with autism have gastrointestinal (GI) disturbances that can complicate clinical management and contribute to behavioral problems. Understanding the molecular and microbial underpinnings of these GI issues is of paramount importance for elucidating pathogenesis, rendering diagnosis, and administering informed treatment. Here we describe an association between high levels of intestinal, mucoepithelial-associated Sutterella species and GI disturbances in children with autism. These findings elevate this little-recognized bacterium to the forefront by demonstrating that Sutterella is a major component of the microbiota in over half of children with autism and gastrointestinal dysfunction (AUT-GI) and is absent in children with only gastrointestinal dysfunction (Control-GI) evaluated in this study. Furthermore, these findings bring into question the role Sutterella plays in the human microbiota in health and disease. With the Sutterella-specific molecular assays described here, some of these questions can begin to be addressed.

Footnotes

      Citation Williams BL, Hornig M, Parekh T, Lipkin WI. 2012. Application of novel PCR-based methods for detection, quantitation, and phylogenetic characterization of Sutterella species in intestinal biopsy samples from children with autism and gastrointestinal disturbances. mBio 3(1):e00261-11. doi:10.1128/mBio.00261-11.

      Received 7 November 2011

      Accepted 9 December 2011

      Published 10 January 2012

      Copyright © 2012 Williams et al.

Gary Null, PhD and Nancy Ashley, VMD, MS - DEADLY INJECTION: THE HIDDEN INGREDIENTS IN VACCINES

DEADLY INJECTION:  THE HIDDEN INGREDIENTS IN VACCINES

By Gary Null, PhD and Nancy Ashley, VMD, MS

For more than 100 years, Americans have lined up to take their vaccines.   We have never questioned the safety and efficacy of these vaccines, and why should we?  Vaccines are backed by the full faith and confidence of the entire scientific community, including the FDA, the CDC, the National Institute of Allergy and Infectious Diseases, and the American Academy of Pediatrics, and virtually all of the esteemed medical journals, including the British Medical Journal, the Lancet, and the Journal of the American Medical Association, have given their unconditional support to vaccines. Therefore, in fact, if any physician, scientist, journalist, or health activist ever challenges either the safety or efficacy of vaccines, they are immediately assaulted.  The normal arguments are:

1. There are dozens of gold standard studies proving beyond a shadow of a doubt the safety and efficacy of every vaccine and every combination of vaccines.
2. There is an independent group of scientists at the FDA and the CDC that examines the childhood vaccine schedule to make sure it is appropriate.
3. There is no scientific proof that vaccines are dangerous.
4. On rare occasions, when someone does have an adverse reaction, it in no way affects the safety and efficacy for anyone else.
5. Virtually all major scourges -- polio, smallpox, and measles -- were eliminated by our vaccine program.

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[Video] Vaccines - The Toxic Truth by Gary Null

Learn the TRUTH about vaccination and the Big Pharma Coverup in this video compilation by Gary Null.