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Recommend "Times of India" - Fountain of youth’s role in brain demystified (Email)

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Times of India | Jul 14, 2011, 03.21pm IST

http://timesofindia.indiatimes.com/life-style/health-fitness/health/Fountain-of-youths-role-in-brain-demystified/articleshow/9223276.cms

A study has found that a fountain of youth that sustains the production of new neurons in the brains of rodents is also believed to be present in the human brain.

The finding by researchers at the Duke University Medical Centre explains why stem cells by themselves can't generate neurons in a lab dish, a major roadblock in using these stem cells for injury repair.

We believe these findings will have important implications for human therapy, Chay Kuo, M.D., Ph.D., George Brumley Jr. assistant professor of Cell Biology, Pediatrics and Neurobiology, and senior author of the study, said.

The scientists found that neighbouring epithelial-like ependymal cells not stem cells themselves maintain a special structure that keeps neural stem cells neurogenic, able to make new neurons.

Currently, when neural stem cells are harvested for growth in culture, however, the ependymal cells are not removed along with them.


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